To use python with client you should write python script. You can specify it from config ("python_script" option) or from command_line [-Z]. You should set the following callbacks in your script: tgl.on_binlog_replay_end() - it is called when replay of old events end. Any updates prior this call were already received by this client some time ago. tgl.on_get_difference_end() - it is called after first get_difference call. So we received all updates after last client execute. tgl.on_our_id(our_id) - Informs about id of currently logged in user. tgl.on_msg_receive(msg) - it is called when we receive new msg (!! may be called before on_binlog_replay_end, than it is old msg). tgl.on_user_update(peer, what_changed) - updated info about user. what_changed is array of strings. tgl.on_chat_update(peer, what_changed) - updated info about user. what_changed is array of strings. tgl.on_secret_chat_update(peer, what_changed) - updated info about user. what_changed is array of strings. Also, you can call several functions. Each this function last two arguments, are callback, which is a python function implementing the callback from the function. These functions may return false immidiately if something is bad with args, or return true and call cb_function in future. The callback function should have one arguments: first success (True or False), and the rest depends on the call. Functions that require a peer type other than what is passed will raise tgl.PeerError. Function_list (arguments are listed aside from callback, import tgl for access) : tgl.get_contact_list () tgl.get_dialog_list () tgl.rename_chat (peer, new_name) tgl.chat_set_photo (peer, file) tgl.send_typing (peer) tgl.send_typing_abort (peer) tgl.send_msg (peer, text) tgl.fwd_msg (peer, msg) tgl.send_photo (peer, file) tgl.send_video (peer, file) tgl.send_audio (peer, file) tgl.send_document (peer, file) tgl.send_text (peer, file) tgl.load_photo(msg) tgl.load_video(msg) tgl.load_video_thumb(msg) tgl.load_audio(msg) tgl.load_document(msg) tgl.load_document_thumb(msg) tgl.info (peer) tgl.get_history (peer, limit) tgl.chat_add_user (peer, user) tgl.chat_del_user (peer, user) tgl.add_contact (phone, first_name, last_name) tgl.rename_contact (phone, first_name, last_name) tgl.msg_search (peer, text) tgl.msg_global_search (text) tgl.mark_read (peer) tgl.set_profile_photo (file) tgl.create_secret_chat (user) tgl.create_group_chat (peer, name) tgl.delete_msg (msg) tgl.restore_msg (msg_id) tgl.status_online () tgl.status_offline () tgl.send_location (peer, latitude, longitude) Additionally, the tgl.Peer object has the following direct methods: peer.rename_chat(new_name) peer.chat_set_photo(file) peer.send_typing() peer.send_typing_abort() peer.send_msg(text) peer.send_photo(file) peer.send_video(file) peer.send_document(file) peer.send_text(file) peer.info() peer.history(limit, offset) peer.add_user(peer) peer.del_user(peer) peer.search(text) peer.mark_read() peer.send_location(latitude, longitude)